Dr. Manzi is Co-Director of the Lupus Center of Excellence and serves as Chair of the Department of Medicine of West Penn Allegheny Health System. She is a Vice Chair and Professor at Temple University.
Dr. Manzi graduated magna cum laude from the University of Notre Dame where she was elected to Phi Beta Kappa and Alpha Epsilon Delta honor societies. She received her medical degree from the University of Pittsburgh School of Medicine where she was elected to Alpha Omega Alpha (AOA), the national medical honor society, and received the Jack Myers Medical Alumni Award at graduation for excellence in exemplifying medical ideals. Dr. Manzi completed her medical internship and residency at Duke University Medical Center where she was appointed Assistant Chief Resident, after which she completed her fellowship in rheumatology at University of Pittsburgh Medical Center, and received her master’s degree in public health from the University of Pittsburgh Graduate School of Public Health.
Dr. Manzi has been named one of the "Best Doctors in America" and one of the "Best 100 Doctors in Pittsburgh." She is recognized nationally and internationally as a leader in lupus patient care and research, and a pioneer in scientific investigation of cardiovascular disease in patients with systemic lupus erythematosus (SLE). Dr. Manzi has served on a number of study sections and currently is a member of the Clinical and Integrative Cardiovascular Sciences Study Section for the National Institutes of Health (NIH). She is the Secretary/Treasurer of the Systemic Lupus International Cooperating Clinics Committee, and a member of the Board of Directors, and the Medical Advisory Committee of the Lupus Foundation of America. She has participated in the design and implementation of many phase I, phase II and phase III clinical trials and her expertise in this area has led to her appointment to the FDA Arthritis Advisory Board and six data safety monitoring boards for NIH intramural and extramural programs.
She has served in numerous leadership roles nationally and internationally including Clinical Chair for the American College of Rheumatology Annual Meeting Planning Committee. She has also appeared several times on ABC TV’s Good Morning America and was recognized by the Pittsburgh Business Times as a “Fast Tracker,” one of the regions 50 front-runners. In 2006 she spoke on lupus advocacy at the Fortune 500 Summit in Las Vegas and was elected as delegate to the Fortune 500 “Most Powerful Women in America.”
She has an extensive national and international patent portfolio with exclusive licensing of lupus biomarker technology to Cypress Biosciences, Inc., in San Diego, CA with the intent to commercialize the technology over the next several years. In recognition of these accomplishments, Dr. Manzi received the Pitt Innovator Award in both 2005 and 2006. Dr. Manzi has been the recipient of millions of dollars in research funding from the NIH and other agencies. She has published more than 100 reports of research in lupus and related diseases.