At AHN, we’re committed to providing our cardiology fellows with rewarding research experiences. We encourage fellows to present at national meetings and submit manuscripts for publication in leading journals. In recent years, several fellows have published peer-reviewed journal articles and have presented numerous abstracts, posters, and oral presentations at local, regional, national and international meetings such as the American Heart Association (AHA) and the American College of Cardiology (ACC).
Program faculty members mentor fellows in a wide range of research interests. We support projects in quality improvement and patient safety. Fellows are allotted one month of research during the first and second years. We urge fellows to initiate projects during this time with completion occurring during the remainder of the training period. All fellows must present their research or quality improvement projects at the end of the year to all faculty.
A unique aspect of research at AHN is the collaborative opportunities available with research scientists at Carnegie Mellon University. Fellows may participate in ongoing projects or initiate new ones in cardiovascular disease.
The Division of Cardiology vigorously supports applications for American Heart Association (AHA) fellowship research grants, as well as funding from other local agencies. Opportunities in basic cardiovascular research are also available at the Cardiovascular Research Institute should any of the trainees be interested.
Riociguat in patients with symptomatic chronic thromboembolic disease (CTED) Multicenter trial to compare clinical outcomes in patients with symptomatic CTED treated with medical therapy versus placebo
Sponsor: Pulmonary Hypertension Accelerated Bayer award
Role: Project PI (Kanwar)
Project period: 2020- 2022
Assessing markers of development of right ventricular failure after LVAD implantation Evaluate variability in baseline levels of RV focused biomarkers to determine if the levels of biomarkers independently contribute to prediction of right heart failure post LVAD implant
Role: PI (Kanwar)
Project period: 2020- 2022
Pulmonary Hypertension Outcomes Risk Assessment (PHORA) This project will develop a versatile decision-support system using machine learning for PAH that integrates comprehensive data sets, data mining and management, user input and complex decision-making.
Sponsor: NIH (R01 HL134674)
Role: Co-I (Kanwar)
Project period: 2016-2020 , extension submitted for 2020-2025
Cardiac Outcomes Risk Assessment (CORA) This project aims to introduce a clinical decision support system using Bayesian Networks for patients undergoing LVAD.
Sponsor: NIH (R01 HL122639)
Role: PI: Murali, Co-I Kanwar
Project period: 2014-2019 (NCS for 2020)
Multicenter study aimed to analyze changes in tissues and serum that are the result of heart failure and LVAD support as well as identify cellular and molecular changes that impact clinical myocardial recovery post LVAD implant
Sponsor: University of Utah
Role: Site PI (Kanwar)
Project period: 2018- 2021
2 center study to determine if soluble protein biomarkers measured before LVAD predict risk of GIB or stroke and after LVAD implant to improve risk discrimination for GIB or stroke. Collaboration with INOVA
Site PI: Kanwar Project period: 2020- 2021
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