The Division of Gastroenterology faculty and fellows annually maintain a wealth of scholarly activity, contributing a wealth of scientific knowledge and clinically significant results to their disciplines. Our division places a high priority on sharing their findings with the scientific community at large. In 2019, the division maintained 17 active research protocols, 50 pipeline protocols, 22 quality improvement projects, and produced 65 peer-reviewed publications. Please find below a representative sample of recent Division publications.
2020: Thakkar S, Kaul V. Endoscopic ultrasound staging of esophageal cancer. Gastroenterol Hepatol. 2020;16:14-20.
2020: Thakkar S, Carleton NM, Rao B, Syed A. Use of artificial intelligence-based analytics from live colonoscopies to optimize the quality of the colonoscopy exam in real-time: proof of concept. Gastroenterology. 2020 Jan 13. pii: S0016-5085(20)30081-0. doi: 10.1053/j.gastro.2019.12.035
2020: Shen B, Kochhar G, Navaneethan U, Farraye FA, Schwartz DA, Lacucci M, Bernstein CN, Dryden G, Cross R, Bruining DH, Kobayashi T, Lukas M, Shergill A, Bortlik M, Lan N, Lukas M, Tang S, Kotze PG, Kiran RP, Dulai PS, El-Hachem S,
Coelho-Prabhu N, Thakkar S, Mao R, Chen G, Zhang S, Suárez BG, Lama YG, Silverberg MS, Sandborn WJ. Practical guidelines on endoscopic treatment for Crohn’s disease strictures: a consensus statement from the Global Interventional Inflammatory Bowel Disease Group. Lancet Gastroenterol Hepatol. 2020; https://doi.org/10.1016/S2468-1253(19)30366-8.
2020: Thakkar SJ, Kochhar GS. Artificial intelligence for real-time detection of early esophageal cancer: another set of eyes to better visualize. Gastrointest Endosc. 2020;91:52-54.
2020: Isaacson M, Babich M. Drug-induced liver injury resources and reporting for the clinician. Clin Liver Dis. 2020;24:131-139. doi: 10.1016/j.cld.2019.09.010.
2020: Parasa S, Wallace M, Bagci U, Antonino M, Berzin T, Byrne M, Celik H, Farahani K, Golding M, Gross S, Jamali V, Mendonca P, Mori Y, Ninh A, Repici A, Rex D, Skrinak K, Thakkar SJ, van Hooft JE, Vargo J, Yu H, Xu Z, Sharma P. Proceedings from the First Global Artificial Intelligence in Gastroenterology and Endoscopy Summit. Gastrointest Endosc. 2020 Apr 25;S0016-5107(20)34198-5.
2020: Matta B, Gougol A, Gao X, Reddy N, Talukdar R, Kochhar R, Goenka MK, Gulla A, Gonzalez JA, Singh VK, Ferreira M, Stevens T, Barbu ST, Nawaz H, Gutierrez SC, Zarnescu NO, Capurso G, Easler J, Triantafyllou K, Pelaez-Luna M, Thakkar S, Ocampo C, de-Madaria E, Cote GA, Wu BU, Paragomi P, Pothoulakis I, Tang G, Papachristou GI. Worldwide Variations in Demographics, Management, and Outcomes of Acute Pancreatitis. Clin Gastroenterol Hepatol. 2020 Jun;18(7):1567-1575.
2020: Syed AR, Carleton NM, Horne Z, Dhawan A, Bedi G, Kochhar G, Morrissey S, Williams H, Atkinson D, Schiffman S, Monga D, Lupetin A, Kirichenko A, Mitre
M, Dhawan M, Kulkarni A, Thakkar S. Survival Trends for Resectable Pancreatic Cancer Using a Multidisciplinary Conference: the Impact of Post-operative Chemotherapy. J Gastrointest Cancer. 2020 Sep;51(3):836-843. doi: 10.1007/s12029-019-00303-z.
2020: Pothoulakis I, Paragomi P, Archibugi L, Tuft M, Talukdar R, Kochhar R, Goenka MK, Gulla A, Singh VK, Gonzalez JA, Ferreira M, Barbu ST, Stevens T, Nawaz H, Gutierrez SC, Zarnescu NO, Easler J, Triantafyllou K, Pelaez-Luna M, Thakkar S, Ocampo C, de-Madaria E, Wu BU, Cote GA, Tang G, Papachristou GI, Capurso G. Clinical features of hypertriglyceridemia-induced acute pancreatitis in an international, multicenter, prospective cohort (APPRENTICE consortium). Pancreatology. 2020 Apr;20(3):325-330. doi: 10.1016/j.pan.2020.02.010.
2020: Lara LF, Silva R, Thakkar S, Stanich PP, Mai D, Samarasena JB. Multicenter case series of patients with small-bowel angiodysplasias treated with a small-bowel radiofrequency ablation catheter. VideoGIE. 2020 Feb 6;5(4):162-167. doi: 10.1016/j.vgie.2019.11.014.
2020: Kochhar GS, Mohy-Ud-Din N, Grover A, Carleton N, Kulkarni A, Farah K, Dhawan M, Thakkar S. EUS-directed transgastric endoscopic retrograde cholangiopancreatography versus laparoscopic-assisted ERCP versus deep enteroscopy-assisted ERCP for patients with RYGB. Endosc Int Open. 2020 Jul;8(7):E877-E882. doi: 10.1055/a-1164-6282.
2020: Carleton NM, Thakkar S. How to Approach and Interpret Studies on AI in Gastroenterology. Gastroenterology. 2020 Apr 6;S0016-5085(20)30463-7. doi: 10.1053/j.gastro.2020.04.001.
2020: Iacucci M, Cannatelli R, Labarile N, Mao R, Panaccione R, Danese, Kochhar GS, Ghosh S, Shen B. Endoscopy in inflammatory bowel diseases during the COVID-19 pandemic and post-pandemic period. Lancet Gastroenterol Hepatol. 2020 Jun;5(6):598-606. doi: 10.1016/S2468-1253(20)30119-9.
2020: Dulai PS, Singh S, Casteele NV, Meserve J, Winters A, Chablaney S, Aniwan S, Shashi P, Kochhar G, Weiss A, Koliani-Pace JL, Gao Y, Boland BS, Chang JT, Faleck D, Hirten R, Ungaro R, Lukin D, Sultan K, Hudesman D, Chang S, Bohm M, Varma S, Fischer M, Shmidt E, Swaminath A, Gupta N, Rosario M, Jairath V, Guizzetti L, Feagan BG, Siegel CA, Shen B, Kane S, Loftus EV Jr, Sandborn WJ, Sands BE, Colombel JF, Lasch K, Cao C. Development and Validation of Clinical Scoring Tool to Predict Outcomes of Treatment With Vedolizumab in Patients With Ulcerative Colitis. Clin Gastroenterol Hepatol. 2020 Feb 13;S1542-3565(20)30174-9.
2020: Chen Y, Yu Q, Farraye FA, Kochhar GS, Bernstein CN, Navaneethan U, Wu K, Zhong J, Schwartz DA, Wu H, Zheng JJ, Iacucci M, Kiran RP, Shen B. Patterns of endoscopy during COVID-19 pandemic: a global survey of interventional inflammatory bowel disease practice. Intest Res. 2020 Jun 2. doi: 10.5217/ir.2020.00037.
2020: Mohan BP, Khan SR, Kassab LL, Ponnada S, Chandan S, Ali T, Dulai PS, Adler DG, Kochhar GS. High pooled performance of convolutional neural networks in computer-aided diagnosis of GI ulcers and/or hemorrhage on wireless capsule endoscopy images: a systematic review and meta-analysis. Gastrointest Endosc. 2020 Jul 25;S0016-5107(20)34633-2.
2020: Bohm M, Xu R, Zhang Y, Varma S, Fischer M, Kochhar G, Boland B, Singh S, Hirten R, Ungaro R, Shmidt E, Lasch K, Jairaith V, Hudesman D, Chang S, Lukin D, Swaminath A, Sands BE, Colombel JF, Kane S, Loftus EV Jr, Shen B, Siegel CA, Sandborn WJ, Dulai PS; VICTORY Collaboration. Comparative safety and effectiveness of vedolizumab to tumour necrosis factor antagonist therapy for Crohn's disease. Aliment Pharmacol Ther. 2020 Jul 13. doi: 10.1111/apt.15921.
2019: Wegner RE, Verma V, Hasan S, Schiffman S, Thakkar S, Horne ZD, Kulkarni A, Williams HK, Monga D, Finley G, Kirichenko AV. Incidence and risk factors for
post-operative mortality, hospitalization, and readmission rates following
pancreatic cancer resection. J Gastrointest Oncol. 2019 Dec;10(6):1080-1093. doi: 10.21037/jgo.2019.09.01.
2019: Syed AR, Thakkar P, Horne ZD, Abdul-Baki H, Kochhar G, Farah K, Thakkar S. Old vs new: risk factors predicting early onset colorectal cancer. World J Gastrointest Oncol. 2019;11:1011-1020.
2019: Syed AR, Carleton NM, Horne Z, Dhawan A, Bedi G, Kochhar G, Morrissey S, Williams H, Atkinson D, Schiffman S, Monga D, Lupetin A, Kirichenko A, Mitre M, Dhawan M, Kulkarni A, Thakkar S. Survival trends for resectable pancreatic cancer using a multidisciplinary conference: the impact of post-operative chemotherapy. J Gastrointest Cancer. 2019; doi: 10.1007/s12029-019-00303-z.
2019: White RJ, Hasan S, Monga D, Finley G, Islam M, Schiffmann S, Williams HK, Kulkarni A, Thakkar S, Kirichenko AV, Wegner RE. Time to adjuvant systemic therapy following pancreatic cancer resection and effect on outcome. Pancreas. 2019;48:1086-1091. doi: 10.1097/MPA.0000000000001367.
2019: Coates MD, Seth N, Clarke K, Abdul-Baki H, Mahoney N, Walter V, Regueiro MD, Ramos-Rivers C, Koutroubakis IE, Bielefeldt K, Binion DG. Opioid analgesics do not improve abdominal pain or quality of life in Crohn's disease. Dig Dis Sci. 2019 Nov 22. doi: 10.1007/s10620-019-05968-x.
2019: Matta B, Gougol A Gao X, Reddy N, Talukdar R, Kochhar R, Goenka MK, Gulla A, Gonzalez JA, Singh VK, Ferreira M, Stevens T, Barbu ST, Nawaz H, Gutierrez SC, Zarnescu NO, Capurso G, Easler J, Triantafyllou K, Pelaez-Luna M, Thakkar S, Ocampo C, Enrique de-Madaria, Cote GA, Wu BU, Paragomi P, Pothoulakis I, Tang G, Papachristou GI. Worldwide variations in demographics, management, and outcomes of acute pancreatitis. Clin Gastroenterol Hepatol. 2019; pii:S1542-3565(19)31272-8. doi: 10.1016/j.cgh.2019.11.017.
2020: Iacucci M, Cannatelli R, Tontini GE, Panaccione R, Danese S, Fiorino G, Matsumoto T, Kochhar GS, Shen B, Kiesslich R, Ghosh S. Improving the quality of surveillance colonoscopy in inflammatory bowel disease. Lancet Gastroenterol Hepatol. 2019 Dec;4(12):971-983. doi: 10.1016/S2468-1253(19)30194-3.
2019: Kochhar G, Wallace M. EUS-guided therapies for solid pancreatic tumors including drug delivery and Brachytherapy. Interventional Endoscopic Ultrasound, 2019, springer publication.
2019: Rao B, Syed A, Sing S, Gulati A, Moussiade G, Garg M, Morrissey S, Williams H, Atkinson D, Schiffman S, Monga D, Lupetin A, Kirichenko A, Mitre M, Tang A, Dhawan M, Kulkarni A, Thakkar S. Performance of a multidisciplinary pancreas cancer conference in predicting and managing resectable pancreatic cancer. Pancreas. 2019;48:80-84. doi: 10.1097/MPA.0000000000001209.
2019: Syed A, Kaul V, Thakkar S. Endoscopic myotomy of Zenker's diverticulum using a novel electrosurgical knife: first reported case in the USA. Dig Endosc.
2019;31:e22-e23. doi: 10.1111/den.13286.
2019: Syed A, Garg M, Patel P, Singh S, Blackwood M, Munigala S, Farah K, Aoun E, Thakkar P, Kulkarni A, Dhawan M, Agrawal S, Wallace D, Thakkar S. Fluoroscopy dose and time characteristics during endoscopic retrograde cholangiopancreatography (ERCP). Surg Laparosc Endosc Percutan Tech. 2019;29:22–25.
2019: Bilal M, Alhajjar O, Madisetty M, Kantamaneni V, Singh S, Babich M, Kapetanos A. Adherence to two large-bore intravenous lines in acute gastrointestinal bleeding is low. Dig Dis Sci. 2019;64:627-631. doi: 10.1007/s10620-019-5455-7.
2019: Smith MS, Cash B, Konda V, Trindade AJ, Gordon S, DeMeester S, Joshi V, Diehl D, Ganguly E, Mashimo H, Singh S, Jobe B, McKinley M, Wallace M, Komatsu Y, Thakkar S, Schnoll-Sussman F, Sharaiha R, Kahaleh M, Tarnasky P, Wolfsen H, Hawes R, Lipham J, Khara H, Pleskow D, Navaneethan U, Kedia P, Hasan M, Sethi A, Samarasena J, Siddiqui UD, Gress F, Rodriguez R, Lee C, Gonda T, Waxman I, Hyder S, Poneros J, Sharzehi K, Di Palma JA, Sejpal DV, Oh D, Hagen J, Rothstein R, Sawhney M, Berzin T, Malik Z, Chang K. Volumetric laser endomicroscopy and its application to Barrett's esophagus: results from a 1,000 patient registry. Dis Esophagus. 2019 Apr 30. pii: doz029. doi: 10.1093/dote/doz029.
2019: Faleck DM, Winters A, Chablaney S, Shashi P, Meserve J, Weiss A, Aniwan S, Koliani-Pace JL, Kochhar G, Boland BS, Singh S, Hirten R, Shmidt E, Kesar V, Lasch K, Luo M, Bohm M, Varma S, Fischer M, Hudesman D, Chang S, Lukin D, Sultan K, Swaminath A, Gupta N, Siegel CA, Shen B, Sandborn WJ, Kane S, Loftus EV Jr, Sands BE, Colombel JF, Dulai PS, Ungaro R. Shorter disease duration is associated with higher rates of response to vedolizumab in patients with Crohn's disease but not ulcerative colitis. Clin Gastroenterol Hepatol. 2019 Nov;17(12):2497-2505.e1. doi: 10.1016/j.cgh.2018.12.040.
2019: Koliani-Pace JL, Singh S, Luo M, Hirten R, Aniwan S, Kochhar G, Chang S, Lukin D, Gao Y, Bohm M, Swaminath A, Gupta N, Shmidt E, Meserve J, Winters A, Chablaney S, Faleck DM, Yang J, Huang Z, Boland BS, Shashi P, Weiss A, Hudesman D, Varma S, Fischer M, Sultan K, Shen B, Kane S, Loftus EV, Sands BE, Colombel JF, Sandborn WJ, Lasch K, Siegel CA, Dulai PS. Changes in vedolizumab utilization across US academic centers and community practice are associated with improved effectiveness and disease outcomes. Inflamm Bowel Dis. 2019 Oct 18;25(11):1854-1861. doi: 10.1093/ibd/izz071.
2019: Arif H, Moussaide G, Kulkarni A, Thakkar S. Hemosuccus pancreaticus and hematochezia - An unusual presentation of a rare disease. Dig Liver Dis. 2019 Apr;51(4):603. doi: 10.1016/j.dld.2018.10.023.
2019: Syed A, Babich O, Thakkar P, Patel A, Abdul-Baki H, Farah K, Morrissey S, Mitre M, Dhawan M, Kochhar G, Kulkarni A, Thakkar S. Defining Pancreatitis as a Risk Factor for Pancreatic Cancer: The Role, Incidence, and Timeline of Development. Pancreas. 2019;48:1098-1101.
2019: Suchniak-Mussari K, Farah K. An Unusual Cause of Upper Gastrointestinal bleeding In A Young Patient. Acta Scientific.
2019: Syed A, Babich O, Rao B, Singh S, Carleton N, Gulati A, Kulkarni A, Garg M, Farah K, Kocchar G, Morrissey M, Mitre M, Kularni A, Dhawan M, Thakkar S. Endoscopic ultrasound-guided fine needle aspiration vs core-needle biopsy for solid pancreatic lesions: comparison of diagnostic accuracy and procedural efficiency. Accepted to Diagn Cytopathol. 2019; 47:1138-1144.
2019: Shen B, Kochhar G, Hull T. Bridging medical and surgical treatment of inflammatory bowel disease: the role of interventional IBD. Am J Gastroenterol. 2019 Apr;114(4):539-540. doi: 10.1038/s41395-018-0416-x.
2019: Meserve J, Aniwan S, Koliani-Pace JL, Shashi P, Weiss A, Faleck D, Winters A, Chablaney S, Kochhar G, Boland BS, Singh S, Hirten R, Shmidt E, Hartke JG, Chilukuri P, Bohm M, Sagi SV, Fischer M, Lukin D, Hudesman D, Chang S, Gao Y, Sultan K, Swaminath A, Gupta N, Kane S, Loftus EV Jr, Shen B, Sands BE, Colombel JF, Siegel CA, Sandborn WJ, Dulai PS. Retrospective analysis of safety of vedolizumab in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2019 Jul;17(8):1533-1540.e2. doi: 10.1016/j.cgh.2018.09.035.
2019: Shen B, Kochhar G, Navaneethan U, Liu X, Farraye FA, Lama YG, Bruining D, Pardi DS, Lukas M, Bortlik M, Wu K, Sood A, Schwartz DA, Sandborn WJ. Role of interventional inflammatory bowel disease in the era of biological therapy: a position statement from the Global Interventional IBD Group. Gastrointest Endosc. Gastrointest Endosc. 2019 Feb;89(2):215-237. doi: 10.1016/j.gie.2018.09.045.
2019: Arif H, Beg M, Zahid S, Sial M, Talwar A, Christou A, Babich M. Refractory hypercalcemia in squamous cell carcinoma of the esophagus-a case report and review of literature. J Gastrointest Cancer. 2019 Dec;50(4):939-942. doi: 10.1007/s12029-018-0124-1.
