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Active Clinical Trials

Short Stay Unit vs Hospitalization in Acute Heart Failure (SSU-AHF)

Active NCT:
Allegheny General Hospital
Allegheny General Hospital

Indiana University

For more information, please contact Kelly Szabo at 412-359-8763 or

Using Short Stay Units Instead of Routine Admission to Improve Patient Centered Health Outcomes for AHF Patients


The majority of the over one million annual AHF hospitalizations originate from the emergency department. Admitting and re-admitting lower risk AHF patients who don't need prolonged hospitalization may increase their risk for poor outcomes and decrease their quality of life: Safe alternatives to hospitalization from the ED are needed. We propose a strategy-of-care, short stay unit management of AHF (i.e. less than 24 hours), will lead to improved outcomes for lower risk AHF patients.

Ages Eligible for Study:  18 Years to 99 Years   (Adult, Older Adult)

Sexes Eligible for Study:  All

Accepts Healthy Volunteers:  No


ED physician clinical diagnosis of AHF;

Planned admission for AHF

Systolic blood pressure > 115mmHg, heart rate < 115bpm, Oxygen saturation > 93% on room air;

Previous history of HF

For Caregiver Burden assessments. The eligibility criteria for a caregiver: 1) person either self-identifies, or when asked identifies themselves, as the primary caregiver for the patient. If there are multiple caregivers, the person who self-identifies as providing the most care will be asked to provide written informed consent.


Transplanted organ of any kind or ventricular assist device patient;

End stage renal disease, on dialysis, or eGFR < 30 mL/min;

Acute coronary syndrome (e.g. EKG changes consistent with ischemia or troponin elevation secondary to ACS);

Other acute co-morbid conditions (e.g. sepsis, altered mental status) that are unlikely to be treated within a SSU stay;

High risk lab values, specifically hemoglobin < 9, sodium < 135

Patients who require ventilatory support of any kind or intravenous vasodilators/vasopressor/inotropic support. Patients who receive a one-time dose of an intravenious vasodiolator, but are no longer on this medication, are eligible.

Pregnant patients or any patient who has been pregnant in the last 3 months

< 18 years of age

Any patient who in the opinion of the clinician or investigator requires hospitalization or ICU level care or will require rehabilitation or skilled nursing after discharge from the ED or hospital

Planned discharge from the emergency department

Patients hospitalized within the last 30 days ONLY if the institution mandates these patients are observed. Otherwise these patients are eligible.

De Novo (new Onset) AHF